An in vivo platform to deliver genetic medicines

An in vivo platform 
to deliver genetic medicines

NanoGalaxy Platform

The NanoGalaxy platform encompasses a library of proprietary non-lipid, hydrophilic polymer nanoparticles (HNPs) that can selectively deliver genetic medicine payloads to the right tissues.

NanoGalaxy Platform Advantages

NanoGalaxy platform’s important advantages over competing technologies:

  • Extra-Hepatic Targeting with Predictable Design

    Targeted delivery to specific cell types and tissues beyond the liver, powered by AI-driven analysis of structure-activity relationships

  • Programmable Immunogenicity

    Tunable chemistry that can either induce immune tolerance or trigger immune activation

  • Payload Versatility

    Compatibility with multiple genetic payloads, including mRNA, siRNA and DNA

  • Scalable Manufacturing

    Chemically synthesizable nanoparticles that are suitable for large-scale manufacturing

Targeted Delivery

The NanoGalaxy® platform is a high-throughput engine designed to overcome the fundamental challenge of genetic medicine: targeted delivery. While traditional lipid nanoparticles (LNPs) are often sequestered by the liver, our library of proprietary Hydrophilic Nanoparticles (HNPs) is engineered to reach many tissues.

Structural Diversity & AI-Driven Discovery

We leverage the vast structural diversity of our HNP library to conduct iterative screening across multiple tissues. Our process is powered by AI-driven Structure-Activity Relationship (SAR) analysis, allowing us to:

  • Predict and Optimize

    Use robust data models to predict nanoparticle behavior with high reliability.

  • Rapidly Iterate

    Interrogate structural diversity at a scale previously impossible through manual screening.

  • Target Diverse Tissues

    Select for specific delivery to the immune system, heart, lung and brain.

AI-Driven Design and Iterative Selection

In Vivo Targeted Delivery